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1.

The Helix Twist: Damage and Repair Follows the DNA Minor Groove.

Kotler, Eran; Segal, Eran.

Cell ; 175(4): 902-904, 2018 11 01.

Artículo en Inglés | MEDLINE | ID: mdl-30388449

2.

Personalized Gut Mucosal Colonization Resistance to Empiric Probiotics Is Associated with Unique Host and Microbiome Features.

Zmora, Niv; Zilberman-Schapira, Gili; Suez, Jotham; Mor, Uria; Dori-Bachash, Mally; Bashiardes, Stavros; Kotler, Eran; Zur, Maya; Regev-Lehavi, Dana; Brik, Rotem Ben-Zeev; Federici, Sara; Cohen, Yotam; Linevsky, Raquel; Rothschild, Daphna; Moor, Andreas E; Ben-Moshe, Shani; Harmelin, Alon; Itzkovitz, Shalev; Maharshak, Nitsan; Shibolet, Oren; Shapiro, Hagit; Pevsner-Fischer, Meirav; Sharon, Itai; Halpern, Zamir; Segal, Eran; Elinav, Eran.

Cell ; 174(6): 1388-1405.e21, 2018 09 06.

Artículo en Inglés | MEDLINE | ID: mdl-30193112

3.

Post-Antibiotic Gut Mucosal Microbiome Reconstitution Is Impaired by Probiotics and Improved by Autologous FMT.

Suez, Jotham; Zmora, Niv; Zilberman-Schapira, Gili; Mor, Uria; Dori-Bachash, Mally; Bashiardes, Stavros; Zur, Maya; Regev-Lehavi, Dana; Ben-Zeev Brik, Rotem; Federici, Sara; Horn, Max; Cohen, Yotam; Moor, Andreas E; Zeevi, David; Korem, Tal; Kotler, Eran; Harmelin, Alon; Itzkovitz, Shalev; Maharshak, Nitsan; Shibolet, Oren; Pevsner-Fischer, Meirav; Shapiro, Hagit; Sharon, Itai; Halpern, Zamir; Segal, Eran; Elinav, Eran.

Cell ; 174(6): 1406-1423.e16, 2018 09 06.

Artículo en Inglés | MEDLINE | ID: mdl-30193113

4.

Deterministic evolution and stringent selection during preneoplasia.

Karlsson, Kasper; Przybilla, Moritz J; Kotler, Eran; Khan, Aziz; Xu, Hang; Karagyozova, Kremena; Sockell, Alexandra; Wong, Wing H; Liu, Katherine; Mah, Amanda; Lo, Yuan-Hung; Lu, Bingxin; Houlahan, Kathleen E; Ma, Zhicheng; Suarez, Carlos J; Barnes, Chris P; Kuo, Calvin J; Curtis, Christina.

Nature ; 618(7964): 383-393, 2023 Jun.

Artículo en Inglés | MEDLINE | ID: mdl-37258665

5.

A Systematic p53 Mutation Library Links Differential Functional Impact to Cancer Mutation Pattern and Evolutionary Conservation.

Kotler, Eran; Shani, Odem; Goldfeld, Guy; Lotan-Pompan, Maya; Tarcic, Ohad; Gershoni, Anat; Hopf, Thomas A; Marks, Debora S; Oren, Moshe; Segal, Eran.

Mol Cell ; 71(1): 178-190.e8, 2018 07 05.

Artículo en Inglés | MEDLINE | ID: mdl-29979965

6.

A Systematic p53 Mutation Library Links Differential Functional Impact to Cancer Mutation Pattern and Evolutionary Conservation.

Kotler, Eran; Shani, Odem; Goldfeld, Guy; Lotan-Pompan, Maya; Tarcic, Ohad; Gershoni, Anat; Hopf, Thomas A; Marks, Debora S; Oren, Moshe; Segal, Eran.

Mol Cell ; 71(5): 873, 2018 09 06.

Artículo en Inglés | MEDLINE | ID: mdl-30193102

7.

RNF20 and USP44 regulate stem cell differentiation by modulating H2B monoubiquitylation.

Fuchs, Gilad; Shema, Efrat; Vesterman, Rita; Kotler, Eran; Wolchinsky, Zohar; Wilder, Sylvia; Golomb, Lior; Pribluda, Ariel; Zhang, Feng; Haj-Yahya, Mahmood; Feldmesser, Ester; Brik, Ashraf; Yu, Xiaochun; Hanna, Jacob; Aberdam, Daniel; Domany, Eytan; Oren, Moshe.

Mol Cell ; 46(5): 662-73, 2012 Jun 08.

Artículo en Inglés | MEDLINE | ID: mdl-22681888

8.

Regulatory module involving FGF13, miR-504, and p53 regulates ribosomal biogenesis and supports cancer cell survival.

Bublik, Débora R; Bursac, Sladana; Sheffer, Michal; Orsolic, Ines; Shalit, Tali; Tarcic, Ohad; Kotler, Eran; Mouhadeb, Odelia; Hoffman, Yonit; Fuchs, Gilad; Levin, Yishai; Volarevic, Sinisa; Oren, Moshe.

Proc Natl Acad Sci U S A ; 114(4): E496-E505, 2017 01 24.

Artículo en Inglés | MEDLINE | ID: mdl-27994142

9.

APOBEC3G protects the genome of human cultured cells and mice from radiation-induced damage.

Britan-Rosich, Yelena; Ma, Jing; Kotler, Eran; Hassan, Faizan; Botvinnik, Alexander; Smith, Yoav; Moshel, Ofra; Nasereddin, Abed; Sharma, Gunjan; Pikarsky, Eli; Ross, Susan; Kotler, Moshe.

FEBS J ; 290(7): 1822-1839, 2023 04.

Artículo en Inglés | MEDLINE | ID: mdl-36325681

10.

Spatial proteomic characterization of HER2-positive breast tumors through neoadjuvant therapy predicts response.

McNamara, Katherine L; Caswell-Jin, Jennifer L; Joshi, Rohan; Ma, Zhicheng; Kotler, Eran; Bean, Gregory R; Kriner, Michelle; Zhou, Zoey; Hoang, Margaret; Beechem, Joseph; Zoeller, Jason; Press, Michael F; Slamon, Dennis J; Hurvitz, Sara A; Curtis, Christina.

Nat Cancer ; 2(4): 400-413, 2021 04.

Artículo en Inglés | MEDLINE | ID: mdl-34966897

11.

Pathologic and molecular responses to neoadjuvant trastuzumab and/or lapatinib from a phase II randomized trial in HER2-positive breast cancer (TRIO-US B07).

Hurvitz, Sara A; Caswell-Jin, Jennifer L; McNamara, Katherine L; Zoeller, Jason J; Bean, Gregory R; Dichmann, Robert; Perez, Alejandra; Patel, Ravindranath; Zehngebot, Lee; Allen, Heather; Bosserman, Linda; DiCarlo, Brian; Kennedy, April; Giuliano, Armando; Calfa, Carmen; Molthrop, David; Mani, Aruna; Chen, Hsiao-Wang; Dering, Judy; Adams, Brad; Kotler, Eran; Press, Michael F; Brugge, Joan S; Curtis, Christina; Slamon, Dennis J.

Nat Commun ; 11(1): 5824, 2020 11 17.

Artículo en Inglés | MEDLINE | ID: mdl-33203854

12.

Functional characterization of the p53 "mutome".

Kotler, Eran; Segal, Eran; Oren, Moshe.

Mol Cell Oncol ; 5(6): e1511207, 2018.

Artículo en Inglés | MEDLINE | ID: mdl-30525089

13.

N-methylation of isopeptide bond as a strategy to resist deubiquitinases.

Haj-Yahya, Mahmood; Eltarteer, Najat; Ohayon, Shimrit; Shema, Efrat; Kotler, Eran; Oren, Moshe; Brik, Ashraf.

Angew Chem Int Ed Engl ; 51(46): 11535-9, 2012 Nov 12.

Artículo en Inglés | MEDLINE | ID: mdl-23065695

14.

p53 mutations promote proteasomal activity.

Oren, Moshe; Kotler, Eran.

Nat Cell Biol ; 18(8): 833-5, 2016 Jul 27.

Artículo en Inglés | MEDLINE | ID: mdl-27463250

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The Helix Twist: Damage and Repair Follows the DNA Minor Groove.

Personalized Gut Mucosal Colonization Resistance to Empiric Probiotics Is Associated with Unique Host and Microbiome Features.

Post-Antibiotic Gut Mucosal Microbiome Reconstitution Is Impaired by Probiotics and Improved by Autologous FMT.

Deterministic evolution and stringent selection during preneoplasia.

A Systematic p53 Mutation Library Links Differential Functional Impact to Cancer Mutation Pattern and Evolutionary Conservation.

A Systematic p53 Mutation Library Links Differential Functional Impact to Cancer Mutation Pattern and Evolutionary Conservation.

RNF20 and USP44 regulate stem cell differentiation by modulating H2B monoubiquitylation.

Regulatory module involving FGF13, miR-504, and p53 regulates ribosomal biogenesis and supports cancer cell survival.

APOBEC3G protects the genome of human cultured cells and mice from radiation-induced damage.

Spatial proteomic characterization of HER2-positive breast tumors through neoadjuvant therapy predicts response.

Pathologic and molecular responses to neoadjuvant trastuzumab and/or lapatinib from a phase II randomized trial in HER2-positive breast cancer (TRIO-US B07).

Functional characterization of the p53 "mutome".

N-methylation of isopeptide bond as a strategy to resist deubiquitinases.

p53 mutations promote proteasomal activity.